Wednesday, September 22, 2021

MSC-Derived Extracellular Vesicles to Heal Diabetic Wounds: a Systematic Review and...

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Abstract Extracellular vesicles from mesenchymal stromal cells (MSC-EVs) have shown promise in wound healing.  Extracellular vesicles are lipid bilayer-delimited particles that are naturally released from...

Sp1-mediated upregulation of Prdx6 expression prevents podocyte injury in diabetic nephropathy...

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Abstract Glomerular podocyte damage is considered to be one of the main mechanisms leading to Diabetic nephropathy. However, the relevant mechanism of podocyte injury is...

Mangiferin inhibits cell migration and angiogenesis via PI3K/AKT/mTOR signaling in high...

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Abstract Mangiferin is a prominent active component that can be derived from several traditional herbs, including Mangifera indica L., Anemarrhena asphodeloides Bge., and Belamcanda chinensis...

Fabrication of In Situ Layered Hydrogel Scaffold for the Co-delivery of...

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Abstract Diabetes mellitus (DM)-associated impairments in wound healing include prolonged inflammation, the overexpression of matrix metalloproteases (MMPs), and low levels of growth factors at the...

Effects of advanced glycation end products on neutrophil migration and aggregation...

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Abstract Increased accumulation of advanced glycation end products (AGEs) in diabetic skin is closely related to delayed wound healing. Studies have shown that the concentration...

Chronic pain with neuropathic characteristics after surgery for major trauma to...

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Abstract The aim of the study wasto identify the prevalence of neuropathic pain after lower limb fracture surgery, assess associations with pain severity, quality of...

Glycation by glyoxal leads to profound changes in the behavior of...

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Abstract Diabetes is a worldwide health problem that is associated with severe complications. Advanced Glycation End products (AGEs) such as Nε-(carboxymethyl)lysine, which result from chronic...

High Incidence of Adverse Outcomes in Haemodialysis Patients with Diabetes with...

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Abstract The aim of the study was to evaluate whether, in subjects receiving haemodialysis (HD), the presence of diabetic foot syndrome (DFS) was associated with...

The Degree of Blood Supply and Infection Control Needed to Treat...

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Abstract Background: Diabetic foot ulcers combined with ischemia and infection can be difficult to treat. Few studies have quantified the level of blood supply and...

Analysis of Glycemic Improvement in Hemodialysis Patients Based on Time in...

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Abstract Introduction: This study aimed to investigate the application value of "time in ranges (TIRs)" in dialysis patients with diabetes and summarize the experience of...