This is a very insightful question, as early cancer detection offers the best chance of cure. Screening exams and careful family history are the best way you and your doctor can go over your health risks and help determine when you should start being screened for particular types of malignancy. In general, it is recommended that men with an average risk of prostate cancer start being screened with a digital rectal exam and PSA blood levels at age 50. There is some evidence that African-American men should start being screened a decade earlier, at age 40. For patients, who have cancer cases in the family, earlier screening may be indicated. Depending upon the pattern of what cancers run in your family, you may be referred to a genetic counselor for further testing. The importance of early screening truly cannot be overemphasized.