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What are the mechanisms of arthritis pain?
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Just as there are different types of arthritis, there are also different types of pain. The arthritis pain you experience can come from various areas of the musculoskeletal system, and your brain can process this information in different ways. Here are the main mechanisms of pain.

Nociceptive Pain

This is the normal mechanism that the body uses to process pain. Nociceptive pain occurs when tiny nerves (nociceptors) that run on the surface of organs, muscles, joints, and throughout the body are stimulated. These messages are carried by nerves to the brain. For example, when you bang your elbow, you feel nociceptive pain.

Mechanical Pain

Nociceptive pain that happens with stretch or pressure in and around joints is called mechanical pain. Osteoarthritis, low back disorders, and tendinitis are common examples of mechanical pain.

Inflammatory Pain

Inflammation is an essential process that helps the body respond to and heal an injury. But it also activates nerves and causes nociceptive pain. When joints are inflamed, damage to bone, muscles, and cartilage (the slick surface between bones of the joints) can occur. Examples of inflammatory arthritis are rheumatoid arthritis, psoriatic arthritis, lupus, gout, and ankylosing spondylitis.

Neuropathic Pain

Neuropathic pain happens when there’s too much or persistent pressure on nerves, or they are damaged. It’s often described as burning, tingling, shooting, stinging, or as “pins and needles.” Some people may describe a stabbing, piercing, cutting, or drilling pain. An example of this type of pain is sciatic pain due to irritation of the sciatic nerve by a disc or bone spur. This pain starts at an area of the spine in the lower back and can run across the hip and buttock and down the leg.

Centralized Pain

Centralized pain was first used to describe pain caused by a damaged central nervous system (brain, brain stem, spinal cord). It is now used to describe any pain that happens when the central nervous system doesn’t work properly and amplifies or increases the volume of pain. Other terms used to describe this condition include “central sensitization,” “central amplification” and “central pain syndrome.” Several common conditions, such as fibromyalgia, irritable bowel syndrome, and temporomandibular joint disorder are some examples. Long-lasting arthritis joint pain can also become centralized.

Psychogenic Pain

Psychogenic pain is an older term for what happens when emotions cause pain in the body, make existing pain worse, or make it last longer. As doctors learn more about how the central nervous system works, fewer types of pain are put in this category. For example, fibromyalgia was once considered psychogenic, but new discoveries have shown problems with pain processing in fibromyalgia. Headache, muscle pain, and low back pain can also be influenced by emotions.

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