Yes, it can. If you’re a professional opera singer, you don’t want to lose that upper register. When women go into menopause, they lose estrogen, but they still usually make the same amount of testosterone. So the ratios change and their voices become a little more masculine.

This is why some women have a deeper voice, a few chin whiskers, and a receding hairline. If it’s a concern, it’s easily treated as long as the hormones are balanced out by replacing some estrogen.