Critical enzymes involved in adipocyte metabolism and function include the following:
- Endothelial-derived lipoprotein lipase – Lipid storage;
- Hormone-sensitive lipase – Lipid elaboration and release from adipocyte depots;
- Acyl-coenzyme A (acyl-CoA) synthetases – Fatty acid synthesis.
In addition, a cascade of enzymes is involved in beta-oxidation and fatty acid metabolism. The ongoing flurry of an investigation into the intricacies of adipocyte metabolism has not only improved our understanding of the pathogenesis of obesity but has also offered several potential targets for therapy.
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