Diets with different macronutrient compositions involve a caloric intake of greater than 1200 kcal/day. This type of diet is designed to reduce the caloric intake by 500-1000 kcal/day from the patient's current dietary intake.

The proposed composition used by the best-validated dietary programs is as follows:

• Protein intake of 0.8-1.5 g/kg of body weight (not to exceed 100 g/day);
• 10-30% of total calories from fat (preferably ≥90% as polyunsaturated fat and < 10% as saturated fat);
• Carbohydrate intake of 50 g/day or more;
• Water intake of 1 L or more;
• Adequate micronutrients and macronutrients.