Many patients lose more than 100 lbs during their first year. Some patients lose weight for more than two years following the procedure and may lose in excess of 200 lbs during that time. Results vary from patient to patient, with the best results coming from those who are committed to lifestyle change. Keep in mind, weight loss surgery isn’t a miracle cure. It’s important to set realistic weight loss goals for yourself right from the start. A loss of about 2 to 3 pounds a week in the first year after the operation is possible, but a pound a week is more likely. You’re aiming for gradual, steady weight loss.