Main idea: natural matrix biopolymer membrane was found to be as effective and safe as the control group treatments. This pilot study suggests natural matrix biopolymer membrane can be used safely to promote ulcer healing.
Abstract
Objective: The aim of this study was to evaluate the therapeutic effects of natural matrix biopolymer membrane (NMBM) in the treatment of venous leg ulcers (VLUs).
Results: In this study, 25 patients with 32 VLUs were included in the final analysis. At four weeks after baseline measurements, the mean percentage change in VLU area of patients in the NMBM group was 61.6% compared with 84.1% for control group patients. Additionally, the mean percentage change in VLU volume of NMBM group patients was 51.2% compared with 84.0% for control group patients. The natural matrix biopolymer membrane group patients exhibited a mean decrease of 0.38 in VAS pain score over four weeks, compared with a mean decrease of 0.13 for control group patients. No significant differences in VLU area , volume or VAS pain score were shown between groups.
Source MAG Online Library
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