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Science Ulcers

The effects of hyperbaric oxygen therapy on diabetic retinopathy: A preliminary study
November 4, 2021
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Main idea: Hyperbaric oxygen therapy may improve diabetic retinopathy and diabetic macular edema. This therapy may serve as an adjunctive treatment in the management of retinal ischemia and capillary hyperpermeability in diabetic retinopathy. Abstract The objective of this study was to prospectively assess the effect of hyperbaric oxygen therapy on diabetic retinopathy lesions and macular […]
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A Randomized, Controlled Clinical Study to Assess the Effect of Anodal and Cathodal Electrical Stimulation on Periwound Skin Blood Flow and Pressure Ulcer Size Reduction in Persons with Neurological Injuries
November 4, 2021
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Main idea: In this study, both electrical stimulation modalities improved blood flow and wound area reduction rate. Studies examining optimal  electrical stimulation treatment times for healing to occur, the effect of comorbidities and baseline wound variables on  electrical stimulation outcomes, and the nature of the relationship between blood flow and healing are necessary. Abstract The […]
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Thrombolytic strategies versus standard anticoagulation for acute deep vein thrombosis of the lower limb
November 4, 2021
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Main idea: Complete clot lysis occurred more frequently after thrombolysis (with or without additional clot removal strategies) and PTS incidence was slightly reduced. Bleeding complications also increased with thrombolysis, but this risk has decreased over time with the use of stricter exclusion criteria of studies. Evidence suggests that systemic administration of thrombolytics and CDT have […]
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Getting the right balance: insole design alters the static balance of people with diabetes and neuropathy
November 4, 2021
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Main idea: Insoles have an effect on static balance but not stepping reaction time. This effect is independent of neuropathy severity. The addition of a textured cover seems to counter the negative effect of an arch fill, even in participants with severe sensation loss. Static balance is unaffected by material softness or resilience. Current best […]
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Effects of Low-Power Light Therapy on the Tissue Repair Process of Chronic Wounds in Diabetic Feet
November 7, 2021
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Main idea: The use of LLLT on chronic wounds in a diabetic foot demonstrated efficacy on the progression of the tissue repair process in a short period. Abstract The objective of the study is to analyze the efficacy of the therapeutic use of Low-Level Laser Therapy (LLLT) on the tissue repair process of chronic wounds […]
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Comparing alternating pressure mattresses and high-specification foam mattresses to prevent pressure ulcers in high-risk patients: the PRESSURE 2 RCT
November 7, 2021
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Abstract Background: Pressure ulcers (PUs) are a burden to patients, carers and health-care providers. Specialist mattresses minimise the intensity and duration of pressure on vulnerable skin sites in at-risk patients. The objective of the study is to develop a new PU of category ≥ 2 in patients using an alternating pressure mattress (APM) compared with […]
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Efficacy and safety of acellular dermal matrix in diabetic foot ulcer treatment: A systematic review and meta-analysis
November 7, 2021
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Main idea: Compared with standard of care, acellular dermal matrix may accelerate the healing velocity of uninfected, non-ischemic, full-thickness diabetic foot ulcer. Acellular dermal matrix showed superiority compared with standard of care alone, while generating no more complications. Abstract Background: Diabetic foot ulcer(DFU) is a chronic, refractory disease in need of multidisciplinary endeavour, miscellaneous strategies […]
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Enzymatic debridement with collagenase in wounds and ulcers: a systematic review and meta-analysis
November 7, 2021
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Main idea: there is very limited data on the effect of collagenase as an enzymatic debridement technique on wounds. More independent research and adequate reporting of adverse events are warranted. Abstract Enzymatic debridement with collagenase is a technique that is commonly used in clinical practice. This systematic review examines the effect of collagenase on all […]
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Diabetes and pressure ulcer risk in hip fracture patients: a meta-analysis
November 7, 2021
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Abstract Objective: The aim of this study was to assess the relationship between diabetes and pressure ulcer (PU) risk in patients with hip fractures. Results: A total of 8 studies with 22,180 patients were included in this study. The mean PU incidence was 15.1% in the group with diabetes compared with 7.5% in the group […]
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Topical and Systemic Effects of N-acetyl Cysteine on Wound Healing in a Diabetic Rat Model
November 7, 2021
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Main idea: The results of this study show that both topical and systemic administration of NAC improved wound healing in a diabetic rat model. This effect of NAC may be related to its antioxidant properties since a reduction in oxidative stress parameters in both tissue and serum were shown in the present study. Abstract Objective: […]
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