Currently set to Index
Currently set to Follow
ask age2b

Allopurinol use and type 2 diabetes incidence among patients with gout: A VA retrospective cohort study

By AGE2B team
March 7, 2021

Anastasia Slobodnick 1 2, Michael Toprover 1 2, Jeffrey Greenberg 2, Daria B Crittenden 2, Virginia C Pike 1 2, Yingzhi Qian 3, Hua Zhong 3, Michael H Pillinger 1 2

Main idea: In this study, allopurinol use was not associated with decreased diabetes incidence.


To assess the impact of allopurinol on diabetes in a retrospective cohort of Veterans Affairs patients with gout. The New York Harbor VA computerized patient record system was searched to identify patients with an ICD-9 code for gout meeting at least 4 modified 1977 American Rheumatology Association gout diagnostic criteria. Over an average of 7.9±4.8 years of follow-up, there was no significant difference in diabetes incidence between the allopurinol and non-allopurinol groups. A lower diabetes incidence in the longest versus shortest quartiles of allopurinol use was attributable to a longer duration of medical follow-up.

Source NIH

Leave a Reply

Ask your question

We read all your emails and your text. Your question will be responded by our specialists, or one of the doctors we're working with, or our community

Please complete the required fields.