Burden of Kidney Disease, Health-Related Quality of Life, and Employment Among Patients Receiving Peritoneal Dialysis and In-Center Hemodialysis: Findings From the DOPPS Program

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Abstract

Individuals faced with decisions regarding kidney replacement therapy options need information on how dialysis treatments might affect daily activities and quality of life, and what factors might influence the evolution over time of the impact of dialysis on daily activities and quality of life.

7,771 Peritoneal Dialysis and In-Center Hemodialysis participants from 6 countries participating in the study.

The scientist analyzedpatient-reported functional status (based on daily living activities), country, demographic and clinical characteristics, and comorbidities.

Results: In both dialysis modalities, Japan had good health state and employment , whereas the US had better mental state, lowest kidney disease burden, and lowest employment. The median change in quality of life was negligible over 1 year in participants completing at least two annual questionnaires.

Conclusions: Variation exists in quality of life, burden of kidney disease, and depression across countries but did not appreciably change over time. Functional status remained one of the strongest predictors of quality of life. Routine assessment of functional status may provide valuable insights for patients and providers in anticipating outcomes and support needs for patients receiving either Peritoneal Dialysis and In-Center Hemodialysis patients.

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