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Science Diabetes mellitus

Type 2 diabetes mellitus increases the mortality risk after acute coronary syndrome treated with coronary artery bypass surgery
November 7, 2021
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Eilon Ram 1 2, Leonid Sternik 3 4, Robert Klempfner 5 4, Zaza Iakobishvili 4 6, Enrique Z Fisman 4, Alexander Tenenbaum 4, Elchanan Zuroff 3 4, Yael Peled 5 4, Ehud Raanani 3 4 Main idea: While type 2 DM did not influence the in-hospital mortality hazard, we showed that the presence of DM […]
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Glucose-lowering drugs or strategies, atherosclerotic cardiovascular events, and heart failure in people with or at risk of type 2 diabetes: an updated systematic review and meta-analysis of randomized cardiovascular outcome trials
November 7, 2021
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We prepared 3 different options for this article, therefore you can choose the option that suits you the most: Original – a scientific text with all terms and abbreviations that scientists usually use; Easy – an option that describes the topic in a general way; Medium – an intermediate version, in which the most difficult […]
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Sotagliflozin in Patients with Diabetes and Chronic Kidney Disease
November 7, 2021
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Deepak L Bhatt 1, Michael Szarek 1, Bertram Pitt 1, Christopher P Cannon 1, Lawrence A Leiter 1, Darren K McGuire 1, Julia B Lewis 1, Matthew C Riddle 1, Silvio E Inzucchi 1, Mikhail N Kosiborod 1, David Z I Cherney 1, Jamie P Dwyer 1, Benjamin M Scirica 1, Clifford J Bailey 1, […]
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Efficacy and Safety of Ertugliflozin in Patients with Overweight and Obesity with Type 2 Diabetes Mellitus
November 7, 2021
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Steven B Heymsfield 1, Annaswamy Raji 2, Silvina Gallo 3, Jie Liu 2, Annpey Pong 2, Hakima Hannachi 2, Steven G Terra 4 Main idea: Meaningful reductions in HbA1c, fasting plasma glucose, BW, and SBP were observed with ertugliflozin in patients with overweight and obesity with type 2 diabetes mellitus. Ertugliflozin improved HbA1c and SBP […]
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Metformin monotherapy for adults with type 2 diabetes mellitus
November 7, 2021
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Filip Gnesin 1, Anne Cathrine Baun Thuesen 2 3, Lise Katrine Aronsen Kähler 4, Sten Madsbad 5, Bianca Hemmingsen 6 Main idea: There is no clear evidence whether metformin monotherapy compared with no intervention, behaviour changing interventions or other glucose-lowering drugs influences patient-important outcomes. Abstract Background: Worldwide, there is an increasing incidence of type 2 […]
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Gut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study)
November 7, 2021
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Yifei Zhang 1, Yanyun Gu 1, Huahui Ren 2, Shujie Wang 1, Huanzi Zhong 2, Xinjie Zhao 3, Jing Ma 4, Xuejiang Gu 5, Yaoming Xue 6, Shan Huang 7, Jialin Yang 8, Li Chen 9, Gang Chen 10, Shen Qu 11, Jun Liang 12, Li Qin 13, Qin Huang 14, Yongde Peng 15, Qi […]
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Comparative Effectiveness of Glucose-Lowering Drugs for Type 2 Diabetes: A Systematic Review and Network Meta-analysis
November 7, 2021
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Apostolos Tsapas 1, Ioannis Avgerinos 2, Thomas Karagiannis 2, Konstantinos Malandris 2, Apostolos Manolopoulos 2, Panagiotis Andreadis 3, Aris Liakos 2, David R Matthews 4, Eleni Bekiari Main idea: In diabetic patients at low cardiovascular risk, no treatment differs from placebo for vascular outcomes. In patients at increased cardiovascular risk receiving metformin-based background therapy, specific […]
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Effect of dulaglutide on cognitive impairment in type 2 diabetes: an exploratory analysis of the REWIND trial
November 7, 2021
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Tali Cukierman-Yaffe 1, Hertzel C Gerstein 2, Helen M Colhoun 3, Rafael Diaz 4, Luis-Emilio García-Pérez 5, Mark Lakshmanan 5, Angelyn Bethel 5, Denis Xavier 6, Jeffrey Probstfield 7, Matthew C Riddle 8, Lars Rydén 9, Charles Messan Atisso 5, Stephanie Hall 10, Purnima Rao-Melacini 10, Jan Basile 11, William C Cushman 12, Edward Franek […]
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Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials
November 7, 2021
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Suetonia C Palmer 1, Britta Tendal 2, Reem A Mustafa 3 4, Per Olav Vandvik 5, Sheyu Li 6 7, Qiukui Hao 8, David Tunnicliffe 9, Marinella Ruospo 10, Patrizia Natale 9 10, Valeria Saglimbene 10, Antonio Nicolucci 11, David W Johnson 12, Marcello Tonelli 13, Maria Chiara Rossi 11, Sunil V Badve 14, Yeoungjee […]
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Safety and efficacy of oral semaglutide versus dulaglutide in Japanese patients with type 2 diabetes (PIONEER 10): an open-label, randomised, active-controlled, phase 3a trial
November 7, 2021
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Daisuke Yabe 1, Jiro Nakamura 2, Hideaki Kaneto 3, Srikanth Deenadayalan 4, Andrea Navarria 4, Mette Gislum 4, Nobuya Inagaki 5, PIONEER 10 Investigators Main idea: Oral semaglutide was well tolerated in Japanese patients with type 2 diabetes. Once-daily oral semaglutide significantly reduced HbA1c (14 mg dose) and bodyweight (7 mg and 14 mg doses) […]
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