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Science Prostate cancer

MRI-Targeted, Systematic, and Combined Biopsy for Prostate Cancer Diagnosis
November 7, 2021
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Michael Ahdoot 1, Andrew R Wilbur 1, Sarah E Reese 1, Amir H Lebastchi 1, Sherif Mehralivand 1, Patrick T Gomella 1, Jonathan Bloom 1, Sandeep Gurram 1, Minhaj Siddiqui 1, Paul Pinsky 1, Howard Parnes 1, W Marston Linehan 1, Maria Merino 1, Peter L Choyke 1, Joanna H Shih 1, Baris Turkbey 1, […]
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Outcomes of Observation vs Stereotactic Ablative Radiation for Oligometastatic Prostate Cancer: The ORIOLE Phase 2 Randomized Clinical Trial
November 7, 2021
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Ryan Phillips 1, William Yue Shi 2, Matthew Deek 1, Noura Radwan 1, Su Jin Lim 3, Emmanuel S Antonarakis 3, Steven P Rowe 4 5, Ashley E Ross 5, Michael A Gorin 4 5, Curtiland Deville 1, Stephen C Greco 1, Hailun Wang 1, Samuel R Denmeade 3, Channing J Paller 3, Shirl Dipasquale […]
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Survival with Olaparib in Metastatic Castration-Resistant Prostate Cancer
November 7, 2021
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Maha Hussain 1, Joaquin Mateo 1, Karim Fizazi 1, Fred Saad 1, Neal Shore 1, Shahneen Sandhu 1, Kim N Chi 1, Oliver Sartor 1, Neeraj Agarwal 1, David Olmos 1, Antoine Thiery-Vuillemin 1, Przemyslaw Twardowski 1, Guilhem Roubaud 1, Mustafa Özgüroğlu 1, Jinyu Kang 1, Joseph Burgents 1, Christopher Gresty 1, Claire Corcoran 1, […]
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Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction
November 7, 2021
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A Hartenstein 1, F Lübbe 1, A D J Baur 1, M M Rudolph 1, C Furth 2, W Brenner 2, H Amthauer 2, B Hamm 1, M Makowski # 1 3, T Penzkofer # 4 5 Main idea: These findings support the role of germline variation contributing to population differences in prostate cancer risk, […]
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Prostate Cancer Nodal Staging: Using Deep Learning to Predict 68 Ga-PSMA-Positivity from CT Imaging Alone
November 7, 2021
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A Hartenstein 1, F Lübbe 1, A D J Baur 1, M M Rudolph 1, C Furth 2, W Brenner 2, H Amthauer 2, B Hamm 1, M Makowski # 1 3, T Penzkofer # 4 5 Main idea: Convolutional neural networks have the potential to build a well performing CT-based biomarker for lymph node […]
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The effect of information on prostate cancer screening decision process: a discrete choice experiment
November 7, 2021
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M Charvin 1, G Launoy 2 3, C Berchi Main idea: The participants attached greater importance to a decrease in the number of false negatives and a reduction in prostate cancer mortality than to other risks such as the number of false positives and overdiagnosis. Further research is needed to help men make an informed […]
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Association Between New Unconfirmed Bone Lesions and Outcomes in Men With Metastatic Castration-Resistant Prostate Cancer Treated With Enzalutamide: Secondary Analysis of the PREVAIL and AFFIRM Randomized Clinical Trials
November 7, 2021
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Andrew J Armstrong 1, Mohammed Al-Adhami 2, Ping Lin 3, Teresa Parli 4, Jennifer Sugg 5, Joyce Steinberg 6, Bertrand Tombal 7, Cora N Sternberg 8, Johann de Bono 9, Howard I Scher 10, Tomasz M Beer 11 Main idea: These results suggest that new unconfirmed lesions detected on follow-up bone scans may represent pseudoprogression […]
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HSD3B1 Genotype and Clinical Outcomes in Metastatic Castration-Sensitive Prostate Cancer
November 7, 2021
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Jason W D Hearn 1, Christopher J Sweeney 2, Nima Almassi 3 4 5, Chad A Reichard 3 4 6, Chandana A Reddy 7 8, Hong Li 8, Brian Hobbs 8, David F Jarrard 9, Yu-Hui Chen 10, Robert Dreicer 11, Jorge A Garcia 12, Michael A Carducci 13, Robert S DiPaola 14, Nima Sharifi […]
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Quality of life in patients with metastatic prostate cancer following treatment with cabazitaxel versus abiraterone or enzalutamide (CARD): an analysis of a randomised, multicentre, open-label, phase 4 study
November 7, 2021
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Karim Fizazi 1, Gero Kramer 2, Jean-Christophe Eymard 3, Cora N Sternberg 4, Johann de Bono 5, Daniel Castellano 6, Bertrand Tombal 7, Christian Wülfing 8, Michael Liontos 9, Joan Carles 10, Roberto Iacovelli 11, Bohuslav Melichar 12, Ásgerður Sverrisdóttir 13, Christine Theodore 14, Susan Feyerabend 15, Carole Helissey 16, Stéphane Oudard 17, Gaetano Facchini […]
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Sequencing of Androgen-Deprivation Therapy With External-Beam Radiotherapy in Localized Prostate Cancer: A Phase III Randomized Controlled Trial
November 7, 2021
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Shawn Malone 1 2, Soumyajit Roy 1 3, Libni Eapen 1 2, Choan E 1 2, Robert MacRae 1 2, Gad Perry 1 2, Julie Bowen 4, Rajiv Samant 1 2, Scott Morgan 1 2, Julia Craig 1, Kyle Malone 2, Scott Grimes 1 Main idea: In our study, there was no statistically significant difference […]
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