Clinical analysis of risk factors for severe COVID-19 patients with type 2 diabetes

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Qianhui Zhang 1, Yanhong Wei 1, Min Chen 1, Qianqian Wan 1, Xiaoqi Chen 2

Main idea: Type 2 diabetic patients were more susceptible to COVID-19 than overall population, which might be associated with hyperglycemia and dyslipidemia. Aggressive treatment should be suggested, especially when these patients had low CD4+T lymphocyte counts and high SAA levels.

Abstract

Aims: To describe characteristics of COVID-19 patients with type 2 diabetes and to analyze risk factors for severity.

Methods: Demographics, comorbidities, symptoms, laboratory findings, treatments and outcomes of COVID-19 patients with diabetes were collected and analyzed.

Results: Seventy-four COVID-19 patients with diabetes were included. Higher levels of blood glucose, serum amyloid A (SAA), C reactive protein and interleukin 6 were associated with severe patients compared to non-severe ones. Levels of albumin, cholesterol, high density lipoprotein and CD4+T lymphocyte counts in severe patients were lower than those in non- severe patients. Logistic regression analysis identified increased SAA levels as risk factors.

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