Hyperuricemia: A Randomized, Placebo-Controlled Trial
Soyeon Lee 1 2, Eun Hye Han 2 3, Sang Ho Lee 2 3, Mi Kyung Lim 4, Chang-O Kim 5, Seongman Kang 1
Main idea: Aster glehni extracts supplementation for 12 weeks did not show significant benefits for reducing serum uric acid concentrations in subjects with mild hyperuricemia.
AGE reduced serum uric acid levels in hyperuricemia rats, but its efficacy in humans has not been explored. The study aimed at investigating the efficacy and safety of AGE on the anti-hyperuricemic effect. Study participants did not show a beneficial effect after six weeks of supplementation with AGE. There were no adverse events reported by subjects or changes in safety parameters after the intervention. The mean changes of secondary endpoints from baseline to each time point did not show significant differences within and between the two groups.