Efficacy and Safety of Chinese Medicine for Obstructive Sleep Apnea: A Protocol for Systematic Review and Meta-Analysis


Main idea: This study provides reliable evidence-based support for the clinical application of Chinese medicine for obstructive sleep apnea.


Background: Obstructive sleep apnea (OSA) is a significant public concern. Clinical practice indicates that Chinese medicine has certain therapeutic advantages, while there is a lack of evidence-based medicine support. The aim of this study is to synthesize related data to explore efficacy and safety of Chinese medicine for OSA.

Data in PubMed, Embase, Web of Science, CNKI, WanFang, VIP databases were comprehensively searched. All the randomized controlled trials (RCTs) in OSA children were identified, in which the effects of Chinese medicine on a range of outcomes were compared.

Results: The efficacy and safety of Chinese medicine for OSA were evaluated in terms of apnea hypopnea index (AHI, the average and lowest blood oxygen, the Epworth Sleep Scale [ESS], and adverse effects).


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