Main idea: The dragon-tiger fighting needling therapy reduces pain symptoms in diabetic neuropathy and increases neuron connectivity.
Abstract: To compare the clinical therapeutic effect on painful diabetic peripheral neuropathy (PDPN) between dragon-tiger fighting needling and pregabalin capsules. A total of 60 patients with PDPN were randomized into an observation group and a control group, 30 cases in each one. Based on treatment with routine anti-hyperglycemic measures and nutritional Neurotherapy, the dragon-tiger fighting needling was exerted at Sanyinjiao (SP 6), Zusanli (ST 36), Yinlingquan (SP 9), and Xuehai (SP 10) in the observation group, once daily. Pregabalin capsules were prescribed for oral administration in the control group, 75 mg, twice a day. The treatment for 2 weeks was as one course and 2 courses of treatment were required in total. The score of the visual analog scale (VAS), the score of MOS item short-form health survey (SF-36), and nerve conduction velocity before and after treatment were compared between the two groups. The clinical therapeutic effect was evaluated in the two groups. After treatment, the VAS score was reduced as compared with before treatment in the two groups. The reducing range of VAS score in the observation group was larger than the control group. After treatment, the sensory nerve conduction velocity (SNCV) and motor nerve conduction velocity (MNCV) of the median nerve and posterior tibial nerve were all improved as compared with before treatment in the two groups. SNCV and MNCV in the observation group were higher than the control group (P0.05). After treatment, the score of each item in SF-36 was increased as compared with before treatment in the two groups and the score of each item in SF-36 in the observation group was higher than the control group. The total effective rate was 86.7% (26/30) in the observation group, better than 60.0% (18/30) in the control group. The dragon-tiger fighting needling therapy relieves painful symptoms, improves the quality of life, and increases nerve conduction velocity in patients with diabetic peripheral neuropathy, and the therapeutic effect is better than oral administration of pregabalin capsules. Keywords: acupuncture dragon-tiger fighter needling nerve conduction velocity painful diabetic peripheral neuropathy quality of life visual analog scale (VAS).