Science Neuropathy

Main idea: The study proves that high-dose vitamin D supplementation can improve symptoms of cardiovascular autonomic neuropathy in Type 1 Diabetes Mellitus patients. The treatment showed no adverse effects, such as hemoglobin level, blood pressure levels, lipids, and insulin dose. Abstract: Cardiovascular autonomic neuropathy (CAN) is associated with diabetes mellitus, increasing morbidity and mortality. Some cross-sectional […]

Main idea: Skin autofluorescence represents a non-invasive, inexpensive, highly reproducible method of measuring AGEs. Increased skin AGEs have been linked with microvascular complications of diabetic neuropathy. In retinopathy, some correlation has been shown between AGEs and the progression of this complication. Additionally, skin AGEs are being increasingly appreciated as predictors of nephropathy. They appear to become […]

Main idea: Patients with inflammatory neuropathies should be encouraged to adhere to the vaccination campaign for COVID-19. These recommendations guide the management of vaccinations for COVID-19 in patients with inflammatory neuropathies. More research is needed regarding the safety and efficacy of vaccination in patients with inflammatory neuropathies and other immune conditions. Abstract: Patients with inflammatory neuropathies should […]

Main idea: Endostatin is a physiological signal molecule that is involved in angiogenesis and impacts neurogenesis. Therapy based on endostatin regulation may lead to improvement of neuropathy symptoms. Abstract: For over a decade, diabetic neuropathy has exhibited great emergence in diabetic patients. There are numerous impediments in understanding the underlying pathology that it is not that enough […]

Main idea: The results showed that most diabetic peripheral neuropathy patients suffer from muscle weakness, pain, loss of balance, and lower limb dysfunction. As a result, their daily activity and life satisfaction are gradually impaired. Exercise therapy, electrotherapy, and other physiotherapy methods have been used to reduce the mentioned cases. Among these interventions, exercise therapy has […]

Main idea: Vitamin D supplementation in patients with painful diabetic neuropathy reduced pain symptoms, enhanced neural connectivity without serious adverse effects. Abstract: In this systematic review and meta-analysis, higher quality data evidence on vitamin D supplementation for painful diabetic neuropathy (PDN) will be provided. Vitamin D supplementation in patients with painful diabetic neuropathy reduced pain symptoms, enhanced […]

Main idea: Mirogabalin was well tolerated and significantly reduced pain levels in diabetic peripheral neuropathic pain and post-herpetic neuralgia treatment. The dose of 7.5 mg once or twice daily was efficient in patients with renal impairment.. Abstract: Overall, 35 patients were enrolled (30 with moderate and 5 with severe renal impairment). Mirogabalin was well tolerated and […]

Main idea: Moxibustion demonstrated promising results in neuropathy treatment.. Abstract: Only 1 study reported that treatment groups experienced no adverse reactions. Toronto Clinical Scoring System indicated a significant decrease in the treatment groups. The other 10 studies did not mention adverse events. Moxibustion therapy may be an effective and safe option for DPN patients but needs […]

Main idea: Inotersen treatment is efficient in neuropathy symptoms reduction in patients with hereditary transthyretin-mediated amyloidosis. Abstract: Hereditary transthyretin-mediated amyloidosis (hATTR) manifests as multisystem dysfunction, including progressive polyneuropathy. Inotersen, an antisense oligonucleotide, improved the course of neuropathic impairment in patients with hATTR in the pivotal NEURO-TTR study. To determine Inotersen’s impact on symptoms and patients” neuropathy experience, […]

Main idea: Combination of acupuncture and mecobalamin are efficient in the treatment of elderly diabetic peripheral neuropathy. Abstract: Although previous studies have reported the effectiveness of acupuncture combined mecobalamin (AM) in the treatment of elderly diabetic peripheral neuropathy (EDPN), no systematic study has assessed its effectiveness and safety. Thus, this study will evaluate the effectiveness and safety […]