Science Neuropathy

Main idea: In regards to the progressive nature of diabetic peripheral neuropathy and the limited time of the combined aerobic and resistance treatment, it seems that the little variations having occurred in KLC-1 serum, aerobic endurance, and trunk strength can be positively taken and evaluated, and although these variations are not statistically significant, it can be […]

Main idea: Nano‐curcumin is superior to placebo in reducing depression and anxiety scores in patients with neuropathy. The nano‐curcumin supplementation was well tolerated. However, further studies with long‐term duration and various doses are required to confirm the results. Abstract: Depression in patients with diabetes is associated with poor glycemic control and linked to an increased risk […]

Main idea: The treatment of neuroinflammation by immune modulation therapy in Chemotherapy-Induced Peripheral Neuropathy may potentially result in clinical benefits in terms of preventing and improving the painful peripheral neuropathy related to chemotherapeutic agents. Abstract: Peripheral neuropathies are characterized by nerve damage and axonal loss, and they could be classified in hereditary or acquired forms. Moreover, neuroinflammatory […]

Main idea: Higher iron stores, the HFE 187C>G variant, and lower hsCRP predicted delayed onset of neuropathy among self-reported white individuals initiating cART. These findings require confirmation but may have implications for cART in HIV+ populations in areas with high endemic iron deficiency, especially those PWH in whom older, more neurotoxic antiretroviral drugs are occasionally still […]

Main idea: Mechanisms of neural ganglia degeneration that leads to sensory neuronopathies development. Among the most crucial genes for risk diagnostics of sensory neuronopathies are RFC-1, FGFR3. Abstract: Degeneration of dorsal root ganglia (DRG) and its central and peripheral projections provokes sensory neuronopathy (SN), a rare disorder with multiple genetic and acquired causes. Clinically, patients with SN […]

Main idea: Mixed connective tissue disease and trigeminal neuropathy are often found together in patients. Mixed connective tissue disease treatment can reduce trigeminal neuropathy progression. Abstract: The present study aims to analyze clinical and laboratory features of mixed connective tissue disease (MCTD)-associated Trigeminal Neuropathy (TN). Clinical records of 12 cases of MCTD-associated Trigeminal Neuropathy diagnosed in Peking […]