Science Mood disorders microbiome

Main idea: psoriasis is connected to gut microbiome disbalance. Abstract The occurrence, progression, and recurrence of psoriasis are thought to be related to mood and psychological disorders such as depression. Psoriasis can lead to depression, and depression, in turn, exacerbates psoriasis. The gut-brain-skin axis has been used to explain correlations among the gut microbiota, emotional states, […]

Main idea: The participation of the main microbial-derived metabolites, also defined as “postbiotics”, such as bile acids, short-chain fatty acids, and tryptophan metabolites in the development of IBD-associated gut and brain dysfunction will be discussed. Abstract The bidirectional communication system existing between the gastrointestinal tract and the brain has a fundamental role in the pathogenesis of […]

Main idea: This study demonstrates that a combination of Bifidobacterium animalis lactis and the well-known prebiotic FOS could be a promising synbiotic strategy to decrease inflammatory status with the improvement of gut disorders in middle-aged people. Abstract Several studies suggest that microbial alterations (dysbiosis) are intimately linked to chronic inflammation occurring upon aging. The aim of […]

Main idea: The current article affirms that pre/probiotic therapy can be beneficial in mood disorders formation. Abstract There is a bidirectional relationship between the brain and the gastrointestinal tract. Foods containing bacteria that positively influence the gastrointestinal microbiome are termed probiotics. Compounds that promote the flourishing of these bacteria are called prebiotics. Whether microbiome influencing therapies […]

Main idea: nutrition-based strategies for gut microbiota modulation are promising fields in mood disorders. Abstract ‘Nutritional Psychiatry’ is an emerging area of research that has great potential as an adjunctive tool for the prevention and treatment of diverse neuropsychiatric disorders. Obesity, dietary patterns, gut microbiome composition, and gut permeability, bioactive food compounds, and nutrients can influence […]

Main idea: Overall, fecal microbiota transplantation of impaired microbiota resulted in enhancing psychiatric-like disturbances (mainly depression and anxiety) in recipient animals, plausibly by impairing the immune system, inflammatory and metabolic pathways, neurochemical processes, and neuro-transmission. On the other side, preclinical and clinical data suggest that reversing or mitigating dysbiosis seems a promising strategy to restore behavioral […]

Main idea: Microbiota homeostasis seems essential for a healthy communication network between gut and brain. Dysbiosis may promote intestinal inflammation, alter gut permeability, and trigger immune reactions in the hunger/satiety regulation center contributing to the pathophysiological development of eating disorders. A restored microbial balance may be a possible treatment target for eating disorders. Abstract There is […]

Main idea: The treatment of bipolar disorder should focus on reducing stress, stress sensitivity, and inflammation by lifestyle changes rather than just temporarily alleviating symptoms with psychopharmacological interventions. Abstract Bipolar disorder is a mental health disorder characterized by extreme shifts in mood, high suicide rate, sleep problems, and dysfunction of psychological traits like self-esteem. It is […]

Main idea: The neurons present in the enteric nervous system interact directly with the neurochemicals produced by the microbiota of the gut, thereby influencing the signaling to the central nervous system. Abstract Psychobiotics are a special class of probiotics that deliver mental health benefits to individuals. They produce or stimulate the production of neurotransmitters, short-chain fatty […]

Main idea: Preliminary data suggest that fecal microbiota transplantation is a potentially safe, well-tolerated, and efficacious treatment for certain conditions other than Clostridium difficile Infection, with evidence for active ulcerative colitis being the most compelling. Abstract The intestinal microbiome has been identified as a key modifier for a variety of health conditions. Fecal Microbiota Transplantation has […]